2021 年のヘルスケア テクノロジー企業トップ 100

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Jul 28, 2023

2021 年のヘルスケア テクノロジー企業トップ 100

L'Healthcare Technology Report presenta la classifica Healthcare Top 100.

The Healthcare Technology Report is pleased to announce The Top 100 Healthcare Technology Companies of 2021. This year's awardees comprise a broad range of companies from well-known names like Johnson & Johnson, 3M Health Care, and Illumina to relatively newer but rapidly growing enterprises such as GRAIL, Capsule, and DNA Script. The diverse range of sophisticated products and services offered through these companies — from digital pharmacies to holistic patient care and AI-powered robotics to digital healthcare payments — have not only led to the modernization of the healthcare sector but also to a brighter future where healthcare is democratized for all.

Advancements in healthcare, whether through data and communications, research and clinical trials, medical devices or consumer offerings, have also helped to create an environment where more promising care alternatives are possible. The pioneering companies selected for this year's list have one thing in common: they are revolutionizing the way we live, and the way we navigate one of the most important factors for us all: our health. The following awardees were nominated and selected based on a thorough evaluation process. Among the key criteria considered were product or service quality, customer adoption, management team caliber, organizational effectiveness, and company growth among other factors.

Please join us in recognizing The Top 100 Healthcare Technology Companies of 2021.

1. Johnson & JohnsonCategory: Medical Devices

Johnson & Johnson engages in the research and development, manufacture and sale of a range of products in the healthcare field. The company operates through three business segments, including consumer, pharmaceutical and medical devices as well as diagnostics.

The medical devices and diagnostics segment includes a range of products distributed to wholesalers, hospitals and retailers. These are used principally in the professional fields by physicians, nurses, therapists, hospitals, diagnostic laboratories and clinics. These products include Cordis' circulatory disease management products, DePuy's orthopaedic joint reconstruction, spinal care and sports medicine products and Ethicon's surgical care and women's health products.

Johnson & Johnson was founded in 1886 and is now ranked No. 36 on the 2021 Fortune 500 list of the largest United States corporations by total revenue. Notably, Johnson & Johnson is one of the world's most valuable companies. Earlier this year, Johnson & Johnson revealed that sales of its medical devices climbed 63% year over year, driven by a greater demand for medical devices, drugs and consumer-health products.

2. Integra LifeSciencesCategory: Medical Devices

Integra LifeSciences is a global leader in neurosurgery. The company offers a broad portfolio of products and solutions for dural access and repair, cerebral spinal fluid management and neuro-critical care. Its regenerative tissue technologies include products that address soft tissue, nerve and tendon repairs and for the treatment of acute and chronic wounds, burns, as well as for plastic and reconstructive surgery.

Founded in 1989 by Richard E. Caruso, the company is headquartered in Princeton, New Jersey. Today, Integra LifeSciences has grown immensely, with over 3000 employees worldwide as well as offices, manufacturing and research facilities in Asia, Australia, Europe, Middle East, and the Americas. Integra products are ubiquitous in many hospital intensive care units and operating rooms around the world. And some of its leading brands include AmnioExcel, Bactiseal, CerebroFlo, Certas Plus, Codman®, CUSA, DuraGen, and DuraSeal.

Recently, Integra posted strong second quarter results, with not only better than expected revenue and much better than expected operating earnings. This year the company has shown a strong recovery from the pandemic, with revenues rising almost 49% year over year in the quarter.

3. SOC TelemedCategory: Healthcare Software

SOC Telemed is headquartered in Reston, Virginia, and is the leading national provider of acute telemedicine technology and solutions to hospitals, health systems, post-acute providers, physician networks, and value-based care organizations since 2004.

Built on proven and scalable infrastructure as an enterprise-wide solution, SOC's technology platform, Telemed IQ, rapidly deploys and seamlessly optimizes telemedicine programs across the continuum of care.SOC clients include 18 of the 25 largest health systems in the nation, and its enabled over 1,000 facilities in 47 states to manage complex, acute workflows and provide life-saving care.

The company provides a supportive and dedicated partner presence, virtually delivering patient care through teleNeurology, telePsychiatry, teleCritical Care, telePulmonology, teleCardiology, teleInfectious Disease, teleNephrology, teleMaternal-Fetal Medicine and other service lines, enabling healthcare organizations to build sustainable telemedicine programs across clinical specialties.

SOC enables organizations to enrich their care models and touch more lives by supplying healthcare teams with industry-leading solutions that drive improved clinical care, patient outcomes, and organizational health.The company was the first provider of acute clinical telemedicine services to earn The Joint Commission's Gold Seal of Approval and has maintained that accreditation every year since inception.

4. Danaher CorporationCategory: Medical Devices

Danaher Corporation designs, manufactures, and markets professional, medical, industrial and commercial products. Founded in 1988, the company has a global network of more than 25 operating companies. However, its acquisitions of companies like Radiometers has seen the company shift towards diagnostics and life sciences. Today, Danaher's life science portfolio stands at $6.95 billion.

At the heart of the company's success is the Danaher Business System (DBS), a set of tools that enables continuous improvement around lean, growth and leadership, based on the Japanese philosophy of "Kaizen."

Founded in 1969 by brothers Steven M. Rales and Mitchell Rales, the company was named after Danaher Creek, following a fishing trip there. Danaher owns about 40 businesses around the world and is currently led by President and CEO Tom Joyce. Steven remains the chairman of Danaher, while Mitch is chairman of the company's executive committee.

This year, Danaher announced its plan to acquire Aldevron, which manufactures plasmid DNA, mRNA, and proteins for biotechnology and pharmaceutical customers, for $9.6 billion.

5. Fresenius Medical CareCategory: Medical Devices

Fresenius Medical Care is a healthcare company focused on providing the highest quality care to people with renal and other chronic conditions. As the world's largest fully integrated renal company, it offers specialty pharmacy and laboratory services, and manufactures and distributes the most comprehensive line of dialysis equipment, disposable products, and renal pharmaceuticals.

Founded in 1996 by Eduard Fresenius (1874-1946) who was a German entrepreneur and pharmacist. Today, the German company cares for more than 345,646 patients in its global network of more than 4,000 dialysis clinics in North America, Europe, Latin America, Asia-Pacific, and Africa. It also operates 44 production sites on all continents, to provide dialysis products such as dialysis machines, dialyzers and related disposables.

Recently, Fresenius announced an expansion of its national efforts with Cigna to improve health outcomes and lower the cost of care for people living with kidney failure, or end stage renal disease. Cigna and FMCNA started working together in 2017 and this new agreement extends the program through at least 2023.

6. NextGen HealthcareCategory: Healthcare Software

NextGen Healthcare is a leading healthcare solutions provider that offers a comprehensive, integrated technology and services platform that supports ambulatory and specialty practices of all sizes. The company develops and sells electronic health record (EHR) software and practice management systems to the healthcare industry. NextGen Healthcare also provides patient engagement, population health, financial management, and clinical solutions for medical and dental practices. Founded in 1974, the company's mission is to empower the transformation of ambulatory care.

In addition to highly configurable core clinical and financial capabilities, the company's portfolio includes tightly integrated solutions that deliver on ambulatory healthcare imperatives including: population health, care management, patient outreach, telemedicine, and nationwide clinical information exchange.

NextGen Healthcare has been on a 5-year transformation that catapulted the company to achieve "Best in KLAS" rankings in dual ambulatory healthcare solution categories (EMR and Practice Management) in 2020. Over this time period, leadership has transformed the company into a market leader with integrated and scalable platforms and an engaged team of executives and employees. The company's strategic acquisitions over the past several years in analytics, telehealth, integrated care and patient experience have materially broadened its portfolio. The company has since grown to have 2,600 employees across the globe with multiple offices including Irvine, California; Horsham, Philadelphia; and Bangalore, India. The company has increased its Net Promoter Scores well above healthcare and technology industry averages. At the same time, the company has improved employee engagement by 33%, jumping well above benchmark and turning NextGen Healthcare into a destination for top talent..

7. Castle Biosciences, Inc.Category: Healthcare Software

Castle Biosciences is a skin cancer diagnostics company focused on providing physicians and patients with personalized, clinically actionable genomic information enabling more accurate treatment plan decisions. Since its inception, the company has applied emerging artificial intelligence techniques in molecular diagnostics to improve patient care and outcomes. The Company's DecisionDx family of molecular diagnostic and prognostic tests have the ability to meaningfully impact how cancers are diagnosed and managed

Founded in 2008 by Derek Maetzold — the current President and Chief Executive Officer — the Friendswood, Texas-based company has grown immensely. Today Castle has 292 employees and operates out of two locations. The company has also experienced rapid success since its initial public offering in 2019. Notably, Castle's revenue in 2020 grew over 20% from 2019, despite the COVID-19 pandemic.

This year, Castle announced its collaboration with the Melanoma Research Foundation (MRF), a non-profit organization leading the melanoma community to transform melanoma from one of the deadliest cancers to one of the most treatable through research, education and advocacy.

8. Boston ScientificCategory: Medical Devices

Boston Scientific is a medical device company with a focus on noninvasive treatment – primarily of cardiovascular, respiratory, neurological, digestive, urological and pelvic conditions. Its first major product was an angioplasty balloon for cardiovascular treatments, introduced in the late-1970s. By 2017, the company had developed more than 13,000 medical products marketed in 100 countries around the world.

For decades, Boston Scientific has worked closely with physicians to develop and introduce single-use technologies to advance patient care across various therapeutic areas. The EXALT Model B Bronchoscope is the latest device to join the company's single-use imaging portfolio alongside the EXALT Model D Single-Use Duodenoscope, LithoVue Digital Flexible Ureteroscope, SpyGlass DS Direct Visualization System and SpyGlass Discover Digital Catheter.

The Marlborough, Massachusetts-based company was founded in 1979 by John Abele and Pete M. Nicholas who wanted to make steerable catheters used in less-invasive medical procedures. Boston Scientific went public in 1992. Today the company has grown tremendously, with over 30,000 employees and 15 offices around the US, including Washington DC, San Diego, Boston and Cambridge.

9. VoceraCategory: Communication Technology

The mission of Vocera Communications is to improve the lives of healthcare professionals, patients, and families. Founded in 2000, Vocera provides solutions that help protect and connect team members, simplify workflows, increase efficiency, enhance quality of care and safety, and humanize the healthcare experience.

More than 2,300 facilities worldwide, including nearly 1,900 hospitals and healthcare facilities, have selected Vocera solutions to enable their workforce to communicate and collaborate with coworkers and engage with patients and families.

Mobile workers can choose the right device for their role or task, including smartphones or one of the company's wearable communication devices, and use voice commands to easily reach people by name, role, or group.

The Vocera Platform can integrate with more than 150 clinical and operational systems, including electronic health records, nurse call systems, ventilators, physiological monitors, and more. In addition to healthcare, Vocera solutions are found in aged care facilities, veterinary hospitals, schools, luxury hotels, retail stores, power facilities, and more.

10. Poseida Therapeutics, Inc.Category: Biotech

Poseida Therapeutics, is a clinical-stage biopharmaceutical company utilizing proprietary genetic engineering platform technologies to create cell and gene therapeutics with the capacity to cure. Poseida's game-changing technologies are advancing the promise of cell and gene therapy to deliver potential single-treatment cures. The company is developing a deep and growing pipeline based on its core proprietary platforms, including its non-viral piggyBac® DNA Modification System, Cas-CLOVER™ site-specific gene editing system and nanoparticle-and AAV-based gene delivery technologies.

Founded in 2014, the San Diego-based company has grown to 225 employees and is led by CEO Eric Ostertag, M.D., Ph.D., a pioneer in cell and gene therapy and the first graduate of the Gene Therapy Program at the University of Pennsylvania School of Medicine.

Poseida's platform technologies offer unmatched efficiency in gene delivery, fully integrated non-viral genome insertion and precise editing. The company's CAR-T product candidates modify the immune system's T-cells to treat multiple myeloma, prostate cancer and other solid tumors like breast, ovarian, colorectal or pancreatic cancers. Poseida also has several liver-directed gene therapy programs focused on the in vivo treatment of rare genetic conditions with high unmet medical need, including ornithine transcarbamylase (OTC) deficiency and hemophilia A.

11. PPDCategory: Biotech

PPD is a global contract research organization that offers drug development, laboratory, and lifecycle management services. PPD applies innovative technologies, therapeutic expertise, and a firm commitment to quality to help customers bend the cost and time curve of drug development to provide life-changing therapies that improve health. Their clients and partners include pharmaceutical, biotechnology, medical device, academic, and government organizations.

Founded in 1985 by Fred Eshelman, the Wilmington, North Carolina-based company has over 27,000 employees. In 2020, PPD issued its initial public stock offering and began trading on the Nasdaq Global Select Market under the symbol PPD.

With more than 28,000 professionals worldwide, PPD has conducted clinical trials in more than 100 countries to help customers deliver life-changing therapies to improve health. We apply innovative technologies, therapeutic expertise and a firm commitment to quality to bend the cost and time curve of drug development and optimize value.

In mid-April, laboratory technology specialist Thermo Fisher Scientific announced its acquisition of global contract research organization PPD in a deal valued at $17.4 billion.

12. GRAILCategory: Healthcare Software

GRAIL is a healthcare company whose mission is to detect cancer early, when it can be cured. The company uses the power of next-generation sequencing, population-scale clinical studies, and state-of-the-art computer science and data science to overcome one of medicine's greatest challenges with Galleri. Galleri is GRAIL's groundbreaking multi-cancer early detection blood test that can detect more than 50 types of cancer, over 45 of which lack recommended screening tests today. Galleri is available in the US.

The company was founded as a spin-out from Illumina and has raised over $2 billion in funding over five rounds. GRAIL has more than 700 employees and is headquartered in Menlo Park, California, with locations in Washington, DC, North Carolina, and the United Kingdom. It is backed by the likes of Bill Gates and Jeff Bezos, and supported by leading global investors and pharmaceutical, technology, and healthcare companies.

GRAIL is currently developing tools to help accelerate cancer diagnoses, blood-based detection for minimal residual disease, and other post-diagnostic applications. Recently, Illumina, the global leader in DNA sequencing, announced that it has acquired GRAIL, reuniting the two companies four years after GRAIL was spun off.

13. Bardy DiagnosticsCategory: ​​Medical Devices

Bellevue, Washington-based company, Bardy Diagnostics, is an innovator in digital health and remote patient monitoring, with a focus on providing the most diagnostically accurate and patient-friendly cardiac patch monitors to the industry. The company's CAM patch is a non-invasive, P-wave centric, ambulatory cardiac monitor and arrhythmia detection device that's designed to improve patient compliance for adults and children.

Designed to be worn comfortably and discreetly for up to 14 days, the hourglass-shaped CAM patch is designed for all types of bodies and for optimum ECG signal collection. The company was founded in 2013, by Gust H. Bardy, a cardiac electrophysiologist since 1983 with research interests in cardiac defibrillator technology, cardiac arrest, ablation, heart failure and atrial fibrillation. He has been a researcher and clinician in the field of sudden death and disabling cardiac rhythm disorders for 38 years with over 400 peer-reviewed publications.

With nearly 300 employees working towards saving patient lives, the company's next step is to distribute a CE-marked 14-day CAM patch outside of the United States. This is one step closer to its P-wave centric detection and analysis technology becoming the global standard of care in long-term cardiac monitoring.

14. 3M Health CareCategory: Medical Devices

3M Health Care is a global leader that offers medical, dental and orthodontic solutions, health information, food safety and drug delivery systems. The company uses 3M technology as well as its world-class manufacturing and global reach to provide trusted products that help promote health and improve the quality, cost and outcomes of care.

While 3M was founded in 1902 with the goal to mine for corundum, a mineral used for making sandpaper and grinding wheels, the company has changed a lot since then. In 1960, the company unveiled its Micropore Surgical Tape, the first hypoallergenic tape on the market. This went on to eventually be the key to its Health Care sector's success.

3M is led by CEO Mike Roman, with Mojdeh Poul, leading as group president of 3M Health Care. This year, 3M's healthcare segment reported $2.3 billion in revenues, which is a 24.9% increase from the second quarter of 2020. Sales in the segment increased in oral care, food safety, medical solutions, separation and purification and health information systems, with growth across all geographic areas.

15. CedarCategory: Healthcare Software

Cedar is a patient payment and engagement platform for hospitals, health systems, and medical groups that elevates the patient experience. The company's mission is to empower us all to easily and affordably pursue the care we need. At a time when consumer-friendly, digital-first experiences are more critical than ever in healthcare, Cedar's financial technology platform is equipped with modern intelligence to solve many of the fundamental problems that lead to poor consumer financial experiences and administrative waste in healthcare. Cedar clients consistently see strong performance—typically a 30% lift in patient payments—with 88% patient satisfaction.

Cedar was founded in 2016 by Arel Lidow, Florian Otto, and Kareem Zaki and is headquartered in New York City. Today, the company engages with more than 300,000 consumers a day, and partners with more than 50 healthcare providers and payers across the US including Yale New Haven Health (YNHHS), Summit Health, Novant Health, ChristianaCare, Blue Cross Blue Shield of Arizona, CommonSpirit Health and Blue Cross Blue Shield of Massachusetts.

Over the last two years, the company has undergone a period of tremendous growth, including raising over $300 million in funding, acquiring OODA Health and being named a top place to work.

16. RapidAICategory: Healthcare Software

From home to hospital and ER to OR, RapidAI is leading the next evolution of clinical decision-making and patient workflow, bringing the end-to-end patient journey into focus. Based on intelligence gained from over 2.6 million scans in more than 1,800 hospitals in over 60 countries, the Rapid® platform transforms care coordination, offering care teams a level of patient visibility never before possible, saving lives, time and money. Founded in 2012 and based in San Mateo, California, RapidAI is the global leader in using AI to combat life-threatening vascular and neurovascular conditions.

The company has seen monumental growth with nearly 1 million scans processed from over 500,000 patients around the world in the first half of 2021 alone. Within this timeframe the company has also introduced new products, including Rapid Workflow for PE, a mobile and web-based app designed to align hospital teams treating patients with suspected pulmonary embolisms. RapidAI also developed RapidforPrehospital, which helps EMS teams and hospitals collaborate to strengthen patient care through a standardized stroke protocol that streamlines data collection.

17. HillRomCategory: Medical Devices

HillRom is an American company focused on medical technologies for the healthcare industry. The company's product portfolio includes patient support systems, safe mobility and handling solutions, non-invasive therapeutic products for a variety of acute and chronic medical conditions, medical equipment rentals, surgical products, and information technology solutions. Our innovations in five core areas – Advancing Mobility, Wound Care and Prevention, Patient Monitoring and Diagnostics, Surgical Safety and Efficiency, and Respiratory Health – improve clinical and economic outcomes and ensure caregivers in more than 100 countries have the products they need to protect patients, speed up recoveries and manage conditions.

Founded in 1929 by William Noah Allyn, the Batesville, Indiana-based company traces its medical innovation roots to when Dr. Francis Welch and Allyn developed the world's first handheld, direct illuminating ophthalmoscope. In 2020, HillRom adapted its respiratory health device MetaNeb to help treat COVID-19 patients. MetaNeb is typically used on patients with pneumonia and attaches to a ventilator and helps to clear the lungs from mucus secretions. In April 2020, Atlanta's Emory University reported the successful use of MetaNeb with coronavirus patients on ventilators.

18. PartsSourceCategory: Medical Devices

PartsSource is the leading B2B marketplace for medtech replacement parts and services. Based in Cleveland, Ohio, the company provides an integrated suite of cloud software and marketplace technology tools to help hospitals efficiently source on-demand parts and services, and empowers vendors to grow their businesses. The company's technology-based solutions help hospitals increase the uptime of mission critical equipment, improve patient safety, and maximize throughput and profitability.

The PartsSource flagship solution, PartsSource Pro, is the only clinical resource management platform for health system enterprises designed to increase the availability and quality of patient care through evidence-based decision support for medical equipment maintenance and purchasing. PartsSource's evidence-based marketplace connects more than 3,500 hospitals, and 15,000 clinics, with more than 6,000 medtech OEMsand suppliers and 2,000 medtech repair professionals across the country in a single integrated network.

The company was founded in 2001, based on the idea that an evidence-based, digital approach to the healthcare supply chain can unlock better healthcare delivery, lower costs, and enhance clinical outcomes.Today, PartsSource is transforming and modernizing healthcare technology supply chains to achieve financial and operational goals.

19. ImagineSoftwareCategory: Healthcare Software

ImagineSoftware is the leading provider of medical billing automation software and revenue cycle management applications. The company offers powerful technology solutions for practices, billing companies, and hospitals. The first products commercialized by ImagineSoftware included HCFA processing and insurance denial mitigation systems. ImagineSoftware solutions improve financial efficiency, build provider reputation, and ultimately enhance the patient experience across 43 specialties, including radiology, anesthesia, pathology, and emergency medicine.

The company was founded in 2000 and is headquartered in Charlotte, North Carolina with additional office locations in California and New York. Today, ImagineSoftware serves more than 75,000 physicians and 47,000 users in all 50 states, the ImagineSoftware product suite boasts $33 billion in charge volume, $800 million in payments processed, and $8.5 billion in collections annually.

Always innovating, ImagineSoftware became one of the first in the industry to implement artificial intelligence (AI) within its product suite. ImagineAI, allows health providers to gather detailed patient demographics and payor information while customizing billing messaging based on patients’ ability to pay their medical bills. The system learns and adjusts over time to maximize revenue without compromising compliance.

20. ImmunexCategory: Biotech

Immunex is a leading biopharmaceutical company dedicated to developing immune system science to protect human health. Applying our scientific expertise in the field of immunology, cytokine biology, vascular biology, antibody-based therapeutics and small molecule research, we work to discover new targets and new therapeutics for treating rheumatoid arthritis, asthma, and other inflammatory diseases, as well as cancer and cardiovascular diseases.

Immunex is best associated with the development of products such as Enbrel, used in the treatment of rheumatoid arthritis; Novantrone, used to treat acute nonlymphocytic leukemia and pain associated with prostate cancer; and Leukine, for use in bone marrow transplant patients.

Founded 1981 by James R. Uhlir and Steven Gillis, the company based in Seattle, Washington. In 2002, Immunex Corporation was acquired by Amgen in a mammoth $16 billion deal. At the time, this deal reflected the growing interest in recently developed biotech drugs and the biotech sector overall.

21. ArdelyxCategory: Biotech

Ardelyx is a biotech company focused on discovering, developing, and commercializing medicines to support patients with kidney and cardiorenal diseases. The company's molecules are known to target transporters and receptors, modulating the uptake of nutrients or inducing secretion of key hormones to help patients. Its lead products include RDX5791, which is being developed both for constipation-predominant irritable bowel syndrome (IBS-C) and for prevention of excess dietary sodium absorption, a new treatment for high blood pressure.

Ardelyx was established in 2007 by Dominique Charmot and Peter G. Schultz with the goal to create novel drugs acting in the GI tract with minimal systemic exposure. Today, the Fremont, California-based company has established agreements with Kyowa Kirin in Japan, Fosun Pharma in China and Knight Therapeutics in Canada for the development and commercialization of tenapanor — a treatment for patients with chronic kidney disease — in their respective territories.

22. DNA ScriptCategory: Biotech

DNA Script is a pioneering life sciences technology company developing a faster and more versatile way to design and manufacture nucleic acids. The company has developed an alternative to traditional DNA synthesis called enzymatic DNA synthesis (EDS). By putting DNA synthesis back in the lab, DNA Script aims to transform life sciences research through innovative technology that gives researchers unprecedented control and autonomy.

Founded in 2015 by Sylvain Gariel, Thomas Ybert, and Xavier Godron, the company is based in Paris, France with an additional office in San Francisco, California. This year, the company has experienced significant traction this year, with the launching of its SYNTAX System in June. Prior to the launch, the SYNTAX System and DNA Script's EDS technology were selected to collaborate on potentially world-changing advances and visionary projects.

DNA Script is collaborating on the development of on-demand therapeutics and diagnostics to address future pandemics through the French Defense Innovation Agency (DGA) as well as through separate partnerships with Moderna and GE Research in support of research grants from the US Defense Advanced Research Projects Agency (DARPA).

23. Syneos HealthCategory: Biotech

Syneos Health is designed to accelerate customer performance to address modern market realities. The company brings together approximately 24,000 clinical and commercial minds with the ability to support customers in more than 110 countries. Together they share insights, use the latest technologies and apply advanced business practices to speed customers’ delivery of important therapies to patients.

Syneos (formerly Inventiv Health) was born out of a $7.4 billion merger between INC Research and inVentiv Health in 2018. Inventiv Health was founded in 1996 while INC Research was established in 1985. Today, Syneos is based in Raleigh, North Carolina and remains as the only fully integrated end-to-end clinical and commercial solution organization.

This year, Syneos revealed that it has expanded its Decentralized Clinical Trial capabilities to include a dedicated Decentralized Clinical Trials Site Advocacy Group, as part of its continuing efforts to move clinical trials closer to the patient. Decentralized Solutions from Syneos Health combines insights, technologies, trial design experience to help transform drug development. It's a revolutionary way that could effectively reduce redundancies, relieve site burden and create more patient journey-informed trial experiences.

24. IBH Integrated Behavioral HealthCategory: Consumer HealthTech

IBH has reimagined mental health and EAP services by investing significantly in data science and digital therapeutics. The result is a comprehensive solution that combines on-demand digital resources with live support by expert clinicians backed by first-class technology for an effective mental health program. The company's proactive, digitally enabled EAP delivers unparalleled access combined with highly personalized care that is precisely customized to each person's preferences. This approach leads to better program outcomes, a healthier and more productive workforce, and true cost savings for its customers.

Founded in 1988, IBH quickly emerged as a trusted behavioral health consultant to large corporations across the nation. Today, the company services more than 38,000 companies, and supports over 8 million people with their mental health.

As one company with one vision, IBH provides innovative, technology-based tools and holistic programs that focus on positive outcomes through clinically validated methods and tools. IBH surrounds users with a full system of support by offering EAP counseling, mental health coaching, digital CBT courses, chronic condition management, and work-life, legal and financial services—all accessible through a single, easy-to-use platform.

25. Pulse BiosciencesCategory: Medical Devices

Pulse Biosciences is a novel bioelectric medicine company committed to health innovation that has the potential to improve and extend the lives of patients. The company's proprietary Nano-Pulse Stimulation™(NPS) technology offers a unique cellular-specific mechanism that has extensive utility across several medical specialties.

The CellFX System is the company's first commercial product to harness the distinctive advantages of NPS technology to address a range of common dermatologic conditions that have generally been challenging to treat with traditional methods. Designed as a multi-application platform, the CellFX System offers customer value with a utilization-based revenue model deployed through a proprietary cloud-based infrastructure.

Pulse Biosciences was founded in 2014, born from the groundbreaking research of nano-pulsed technology breakthroughs discovered by leading bioelectric researchers at Old Dominion University and the University of Southern California. The company is headquartered in Hayward, California and to date, Pulse Biosciences holds more than 112 issued licensed patents worldwide. This year, the CellFX System received U.S. FDA clearance, the CE Mark for commercialization in the European Union and a Medical Device License from Health Canada.

26. AlltechCategory: Biotech

Alltech is a global animal health company providing natural, nutritional supplements for livestock and poultry producers. Through its innovative study of nutrigenomics, the company's nutritional technologies help animals maximize the nutrients in their feed for optimal well-being and performance. Alltech works with producers across the globe to address important animal nutrition issues and helps them to increase their efficiency, productivity and profitability through analytical services.

Alltech was founded in 1980 by Dr. Pearse Lyons, who moved to the US in the 70s with a dream to help sustain the planet and all that lived on it. Today, The Nicholasville, Kentucky-based company has amassed a global team of more than 5,000 people who help to improve plant, feed and food quality through nutrition and scientific innovation, particularly yeast-based technology.

This year, Alltech launched Acutia, a wholly owned subsidiary of Alltech, which combines science and sustainability to provide high-quality supplements that enhance everyday nutrition and improve long-term wellness. Acutia's initial line of products will be rolled out in phases, beginning with Acutia Selenium and later Acutia Digestive Health. In 2019, researchers with Alltech Life Sciences achieved a breakthrough that offers a possible alternative to current insulin treatments for those living with diabetes.

27. BioDelivery Sciences International IncCategory: Biotech

BioDelivery Sciences International is a commercial-stage specialty pharmaceutical company dedicated to patients living with chronic conditions. The company uses their novel and proprietary BioErodible MucoAdhesive (BEMA) drug delivery technology to develop and commercialize, either on their own or in partnership with third parties, new applications of proven therapies aimed at addressing important unmet medical needs.

Founded in 1997 and headquartered in, today BioDelivery Sciences has 170 employees. BioDelivery's marketed products — and those in development — address serious conditions such as breakthrough cancer pain, chronic pain, painful diabetic neuropathy and opioid dependence. It looks to improve upon existing drugs by enhancing their efficacy and ease of administration, or create new therapies, all with the ultimate goal of enhancing patient care.

28. QventusCategory: Healthcare Software

Qventus is the first real-time operations system for healthcare. Building on formative experiences at Stanford and McKinsey, Qventus was founded in 2012 with the belief that world-class healthcare requires first class operations.

Integrating with EHRs, the Qventus real - time automation platform uses AI and behavioral science to power best practice solutions for operational challenges in inpatient, ED, perioperative, and command center settings. To operationalize the software, the Qventus Expert Services helps establish governance, deploy the solutions, and drive change management.

With backing from leading investors including Bessemer Venture Partners, Norwest Venture Partners, and the Mayfield Fund, the company is developing a complete system for transforming the operations of health systems and hospitals nationwide.

Qventus is a proven partner with hundreds of deployments in community hospitals, academic medical centers, and large health systems across the country, including Bon Secours Mercy Health, CommonSpirit Health, HonorHealth, M Health Fairview, and Saint Luke’ s Health System. With Qventus, these systems have been able to achieve significant and sustained outcomes, including 90% lower excess days per patient.

29. Biocon BiologicsCategory: Biotech

Biocon Biologics is a fully-integrated pure-play biosimilars organization globally engaged in developing high-quality, affordable biosimilars aimed at expanding patient access to cutting-edge therapies. It develops and commercializes a differentiated portfolio of novel biologics, biosimilars, and complex small molecule APIs in India and several key global markets, as well as generic formulations in the US and Europe.

Founded 1978 by Kiran Mazumdar-Shaw, the company is driven by a belief that the pharmaceutical industry has a humanitarian responsibility to provide essential drugs to patients who are in need and to do so with the power of innovation. In 1979, just a year after being established, Biocon became the first Indian company to manufacture and export enzymes to USA and Europe

Today, Biocon has a large portfolio of biosimilars under global clinical development with three of these commercialized in at least one of the developed markets of Europe, US, and Japan. Biocon Biologics has a product pipeline of 28 molecules, including 11 with Mylan, several with Sandoz and is developing many independently.

30. PaxeraHealthCategory: Healthcare Software

PaxeraHealth Corp is a world leading innovative medical imaging solution developer, designing next generation technology to elevate patient care and improve clinical, financial, and operational outcomes. PaxeraHealth has been at the forefront of artificial intelligence (AI) development for the medical imaging industry, utilizing AI technology at the core of their solutions.

Founded in 2009, PaxeraHealth has expanded to over 140 employees in 10 countries, with its head office in Boston, Massachusetts and an active dealer network in over 45 countries. This year, the company is launching PaxexaUltima 8th Generation, an artificial intelligence (AI)-based imaging platform. It provides cutting edge AI algorithms to analyze large data sets, prioritize studies, and provide support for clinical analysis. Additionally, the intelligent platform enables healthcare systems to self-develop AI algorithms based on their own data sets.

Built from the ground up, the 8th generation AI-based imaging platform offers a viable solution to clinical, economic, and volume-based challenges. The native cutting-edge AI algorithms concurrently aid with analyzing large sets of data, prioritizing high-risk studies, decreasing reading times, and reducing false positives and costly patient recalls.

31. b.well Connected HealthCategory: Consumer HealthTech

B.well Connected Health offers digital technology for health information and empowers consumers to manage all of their healthcare in one location. The b.well Connected Health platform — which they call the "new front end" of healthcare — can be enabled to collect and aggregate their healthcare data across providers, insurance companies, labs, pharmacies and Medicare, as well as any third-party app, wearable or device, and to share it with whomever they choose. It specializes and supports health plans, health systems, employers and pharmaceutical companies.

The company was founded by Bryan Jones and Kristen Valdes in 2015 and is headquartered in Baltimore, Maryland. Since then, the company has grown significantly and is contracted to support over 7 million people.

This year, b.well Connected Health announced it had raised an oversubscribed financing round. The funding round followed a strong year of growth in 2020–21, which saw business double as more organizations implemented the b.well platform to connect with their patients, employees and communities.

32. Cerexa Inc.Category: Biotech

Cerexa is a biopharmaceutical company that produces a portfolio of anti-infective therapies for the treatment of life-threatening infections. The company's product portfolio includes Ceftaroline AcetateCeftaroline, an injectable cephalosporin that is used for the treatment of bacterial infections caused by gram-positive and gram-negative pathogens.

Founded in 2005 by Dennis Podlesak and James Ge, Cerexa was a spin-out from Peninsula Pharmaceuticals and went on to become acquired by Forest Laboratories in 2007 for $500 million. Forest was later acquired by Allergan (formerly Actavis) in 2014.

Allergan, is a multi-specialty healthcare company focused on discovering, developing and commercializing innovative pharmaceuticals, biologics and medical devices that enable people to live life to its greatest potential to see more clearly, move more freely, express themselves more fully. Founded in 1950 by pharmacist Gavin S. Herbert Allergan focused on the discovery and development of novel formulations for specialty markets, as well as intimate collaboration with physicians and the scientific community.

33. Genuity ScienceCategory: Biotech

Genuity Science is a biotechnology company that uses leading genomics and machine learning to map the causal biology of disease and accelerate the development of better medicine. Genuity partners with global biopharma companies to offer deep end-to-end discovery services aimed at catalyzing precision health and improving the quality of life for patients around the world. Its services include population-scale, disease-specific data sourcing, high-quality sequencing, robust statistical analysis and software tools for analyzing large datasets and artificial intelligence (AI).

Founded in 2013 and headquartered in Boston, Massachusetts, Genuity has grown to have more than 100 employees. This includes over 70 experts in molecular biology, population genomics, oncology, neurology, computational and systems biology, clinical genetics, AI and machine learning.

This year, Genuity Science launched the Genuity AI Research Institute (GAIRI), a collaborative research and development platform. GAIRI is led by Chief Technology Officer, President and Founding Director Tom Chittenden, Director of Computational Biology Tiago Magalhaes, Director of Computational Statistics Jose Malagon Lopez, and Director of Bioinformatics Allison McLean. GAIRI is designed to accelerate the development and application of AI and machine learning solutions to medicine and healthcare.

34. AKASACategory: Healthcare Software

AKASA is an AI-powered automation company for revenue cycle management in healthcare. The company is propelled by its mission that "every dollar spent on healthcare matters because healthcare matters to everyone." Motivated to demystify the complexity of American healthcare, AKASA enables health systems to decrease their cost to collect so they can invest more in patient care and better invest in providing healthcare using the same machine learning approaches that made driverless cars possible.

Founded in 2018 by Andy Atwal, Benjamin Beadle-Ryby, Malinka Walaliyadde and Varun Ganapathi, the San Francisco company is led by pioneering Silicon Valley leaders who have founded or been founding team members of multiple companies with successful exits. The company also includes senior leaders in healthcare as well as a deep well of talent from healthcare services firms like the Advisory Board, Optum and Triage Consulting.

This year, AKASA announced that it had raised a funding round, tripling its prior round in 2020. The company plans to use the funding to invest in talent, scale operations to meet rapidly growing customer demand, and continue to accelerate delivery of products to customers. Its investors include Andreessen Horowitz, BOND and Costanoa Ventures.

35. Imclone SystemsCategory: Biotech

ImClone Systems is a fully integrated global biopharmaceutical company committed to advancing oncology care. The company is focused on developing and commercializing a portfolio of targeted biologic treatments designed to address the medical needs of patients with a variety of cancers. ImClone's research and clinical development capabilities are augmented by its expertise in the scale-up and manufacturing of biologics. The company's state-of-the-art FDA-approved manufacturing facilities in Branchburg, New Jersey, provide it with one of the largest biologic manufacturing capacities in the world.

Founded in 1984 by Samuel D. Waksal, the company was acquired by Eli Lilly and Company in 2008 and became a fully-owned subsidiary of Eli Lilly and Company. Following its acquisition by Eli Lilly and Company in 2008, ImClone Systems is accelerating its antibody pipeline development by leveraging Lilly's global capabilities. ImClone's pipeline has several molecules in mid- to late-stage clinical development targeting virtually all major solid tumor types. Additionally, ImClone plans to advance several additional targets from its research programs into clinical development over the coming years.

36. Neptune Wellness SolutionsCategory: Consumer HealthTech

Neptune Wellness Solutions is a health and wellness company focused on extraction, formulation, and packaging of legal cannabis products. The company specializes in three main areas of cannabis and industrial hemp extraction, turnkey solutions, and consumer brands.Its current manufacturing includes natural products in the pet supplement, nutrition, hemp,and krill oil industries. With its scientific and technological expertise, Neptune aims to redefine health and wellness through social responsibility, sustainability, and innovation for all generations.

Founded in 1998 by Henri Harland, the formerly Quebec, Canada-based company recently moved its headquarters to South Florida. The company is currently led by Michael Cammarata, who grew up in Florida, and is the co-founder and former CEO of Schmidt's Naturals, which he sold to Unilever for an undisclosed amount in 2017.

Today, Neptune's brands include Biodroga Nutraceuticals, MaxSimil, Organic Foods & Beverages, Beauty & Personal Care, Forest Remedies, Ocean Remedies, Neptune Wellness, Mood Ring, PanHash, Sprout, NurturMe, and Nosh. Under the Forest Remedies brand, Neptune offers a full line of health and wellness products with and without cannabidiol.

37. Phathom PharmaceuticalsCategory: Biotech

Phathom Pharmaceuticals is a late clinical-stage biopharmaceutical company committed to transforming the treatment landscape and improving the lives of patients suffering from acid-related gastrointestinal (GI) disorders. The company is pushing the limits of what's possible to awaken a dormant category that has lacked innovation for nearly 30 years working to usher in a new era of treatment for the millions of underserved patients suffering from acid-related disorders.

Phathom has licensed the exclusive rights in the U.S., Europe, and Canada to vonoprazan, a potassium competitive acid blocker (P-CAB) in late clinical-stage development for the treatment of gastric acid-related disease. Vonoprazan has the potential to be a paradigm shift in GI treatment and the first gastric antisecretory agent from a new class approved in the U.S., Europe, or Canada in over 25 years. Phathom's IPO was completed in October 2019 and currently has a market cap of over $1 billion. Despite the global pandemic, Phathom skillfully navigated uncertain circumstances to safely continue its global clinical trials.

38. Meda BiotechCategory: Biotech

Meda Biotech is a clinical-stage biopharmaceutical company developing a new class of hybrid water-soluble drugs. These drugs have unprecedented control over its properties to maximise delivery to disease sites, dramatically enhancing efficacy while minimising toxicities. Meda also develops Hybrid water soluble drugs in collaboration with pharmaceutical and biotechnology partners to enable promising pipeline candidates to achieve their full potential. Founded in 2003, Media is composed of researchers who are extremely eager to discover and develop additional game changing therapeutics.

The company has been working to commercialise a technology that could make treatment more effective and less harmful to patients, especially for the treatment of cancer, pain and inflammation. Meda Biotech is developing a pipeline of novel hybrid drugs that hold the potential to become best-in-class drugs and improve patient outcomes in the areas of oncology, inflammatory diseases and cardiovascular and GI disorders. Meda's lead product candidate, Mewa001 (Aspirin) is currently in Phase 1 clinical testing in cancer patients for pain and inflammation.

39. Vesta HealthcareCategory: Consumer HealthTech

Vesta Healthcare's unique "Homecareist" model offers an integrated, patient and caregiver centered program that connects caregiver insights, technology tools and telehealth services all under the supervision of a virtual physician group - all with the aim of enabling their members to have more healthy days at home. Using Remote Patient Monitoring devices, Personal Emergency Response Systems (PERS), a proprietary mobile app and other technologies, Vesta captures real - time insights from home - based caregivers.

As insights are gathered, Vesta's team of clinicians provide 24/7 support by providing virtual care, mobilizing appropriate clinical intervention, educating paid and unpaid caregivers, and coordinating follow - up care with physicians and care managers. In addition to improved quality metrics, reductions in total costs of care, and tighter integration of healthcare and SDoH needs, Vesta's programs have reduced Emergency Room visits and Hospital Admissions by over 30% and enabled 94% of follow - up care for its members to be delivered in the community rather than a facility.

Vesta Healthcare was founded in New York, NY in 2018, with investment from Oak HC/FT, Deerfield Management, Optum Ventures, Kaiser Permanente Ventures, Lux Capital, Generator Venture s and Nationwide Ventures. With over 50 different Health Plan, Home Care Agency and Provider partners, Vesta currently serves over 50,000 members through its programs.

40. PromaxoCategory: Medical Devices

Promaxo is commercializing customer-centric MRI systems and robotic guidance tools for live diagnosis and treatment in a physician's office. The company was founded in 2016 by Amit Vohra, Michael Bartholomew, and developed by a team of entrepreneurs and healthcare innovators into a minimally invasive and patient centric MRI and robotic platform. Based in Oakland, California, and backed by over 90 patents, the company's mission is to improve lives through state of the art medical imaging, robotics and AI capabilities.

With a compact and adaptable MRI, Promaxo is redefining the standard of care by improving the quality and speed of patient diagnosis and interventions. Recently, the Company received 510(k) clearance from the U.S. FDA for its revolutionary office - based MRI system, allowing practices and hospitals to seamlessly guide prostate interventions under the single - sided scanner. Promaxo has formed numerous long-term and strategic partnerships with investor groups and corporations as it prepares to enter the US market.

41. Pall Life SciencesCategory: Biotech

Pall Corporation is a global leader in high-tech filtration, separation, and purification, serving the diverse needs of customers across a wide range of applications. The company provides cutting-edge products and services to meet the demanding needs of customers discovering, developing and producing biotech drugs, vaccines, cell therapies and classic pharmaceuticals.

Pall offers advanced medical technologies, which are often a patient's last line of defense from dangerous pathogens. Pall's food and beverage products provide critical protection from contaminants during various manufacturing steps.

Founded in 1946, Pall has a strong track record of innovation and performance. Since joining Danaher, Pall has continued to drive innovation, developing everything from a mobile water treatment portfolio to an advanced filtration membrane for wet chemical processing.

This year, Cytiva and Pall — both of which are part of Danaher — said they’ll expand manufacturing capacity and services across geographies for global life sciences customers. The $1.5 billion two-year investment is already underway. The deal includes new sites, expansion at existing factories, and is in addition to previously announced investments.

42. MixlabCategory: Consumer HealthTech

Mixlab is a modern, pet pharmacy, based in New York and Los Angeles, that partners with veterinarians to make their jobs easier and deliver the highest level of care to pet parents. The company was built upon three core values —#makeithappen, #dowhatsright and #mixedwithlove. The Mixlab team does everything that it takes to deliver the best personalized care to pets, in the fastest and most humane way possible.

Mixlab's technology includes a platform that manages the home delivery of medications across branded, generic and over-the-counter medications, which helps to reduce a clinic's on-site pharmaceutical inventory. Veterinarians can write prescriptions in seconds and track medication progress and therapy compliance.

Mixlab was founded in 2017, by Fred Dijols, Vinnie Dam, and Stella Kim, with the goal to provide a better pharmacy experience, with the veterinarian at the center. Dijols’ background is in medical devices as well as healthcare investment banking, where he became interested in the pharmacy industry, following TruePill and PillPack.

43. Edwards LifesciencesCategory: Medical Devices

Edwards Lifesciences is the global leader in the science of heart valves and hemodynamic monitoring. The company partners with clinicians to develop innovative technologies in the areas of structural heart disease and critical care monitoring that enable them to save and enhance lives. Notably, Edwards developed the SAPIEN transcatheter aortic heart valve made of cow tissue within a balloon-expandable, which was FDA-approved for the treatment of patients at low risk for death or major complications associated with open-heart surgery in 2019.

Edwards was founded by engineer Miles "Lowell" Edwards in 1958. Today, the Irvine, California-based company has over 3000 employees, with additional offices located in Utah and Singapore as well as numerous commercial operations across the globe.

This year, Edwards announced that it has established a Social Impact Investment Fund to advance racial equity in healthcare. The $100 million fund is a portfolio of investments aimed at advancing racial equity through economic development in Black and underserved communities in the US. It has already committed $70 million of its $100 million fund to provide additional capital for targeted programs, economic initiatives and community development projects.

44. SleepHive (formerly Revitalife)Category: Medical Devices

SleepHive, formerly Revitalife, is an industry leading medical devices company specializing in high performance sleep. The company produces a premium range of therapeutic products for everyone from elite athletes to people over the age of 60. There's a focus on innovative technology SleepHive looks to shape the waking lives of our customers by shaping their resting lives.

SleepHive is an Australian family-owned and operated class 1 medical devices company specialising in innovative therapeutic products for everyone, from elite athletes to senior Australians. As a registered National Disability Insurance Scheme (NDIS) provider SleepHive works closely with leading health and medical professionals, with the mission to help more Australians suffer less, enjoy faster recovery and attain restful sleep.

With distribution centres in Sydney, Melbourne, Adelaide and Perth, and a head office and showroom on the Gold Coast, the "therapeutic sleep systems" manufacturer SleepHive is a big operation.

SleepHive offers one-on-one personalised consultations, both in-home and online, to work with customers in building a sleep solution that works best for their unique needs and requirements.

45. Illumina, Inc.Category: Biotech

Illumina is a biotech company focused on applying innovative technologies and revolutionary assays to the analysis of genetic variation and function, making studies possible that were not even imaginable just a few years ago. As a company that places a high value on collaborative interactions, rapid delivery of solutions, and prioritizing the needs of its customers, they strive to meet this challenge. Illumina's innovative, array-based solutions for DNA, RNA, and protein analysis serve as tools for disease research, drug development, and the development of molecular tests in the clinic.

Illumina was founded in San Diego, California in 1998 by David R. Walt, Satnam Alag, Larry Bock, and John Stuelpnagel. By 2014, the company claimed its technology had reduced the cost of sequencing a human genome to US$1,000, down from a price of $1 million in 2007.

Recently, Illumina's CEO Francis deSouza revealed that a 78% increase in second-quarter sales over 2020 "significantly exceeded expectations." That amounts to $1.13 billion in revenue, resulting from DNA-based cancer screening and population genomics testing efforts returning to business as usual, as well as the company's COVID-19 surveillance programs, which use genetic sequencing to trace the spread of new variants.

46. ResMedCategory: Medical Devices

ResMed provides medical equipment for treating, diagnosing, and managing sleep-disordered breathing and other respiratory disorders. The company pioneers innovative solutions that treat and keep people out of the hospital, empowering them to live healthier, higher-quality lives. Its cloud-connected medical devices transform care for people with sleep apnea, COPD, and other chronic diseases. Its comprehensive out-of-hospital software platforms support the professionals and caregivers who help people stay healthy in the home or care setting of their choice.

ResMed was founded in 1989 by Michael Farrell and is headquartered in San Diego, California. Its team of over 8,000 employees makes a positive impact on millions of lives every day in more than 140 countries. The company has a goal to change the lives of 250 million people by 2025.

This year, ResMed announced the release of the AirSense 11, its latest CPAP machine iteration, which includes a host of new features to treat obstructive sleep apnea. ResMed is launching the AirSense 11 starting in the U.S., and expects to add more locations. It is compatible with all of the company's existing masks, according to the announcement.

47. QIAGENCategory: Biotech

QIAGEN is a German provider of sample and assay technologies for molecular diagnostics, applied testing, academic and pharmaceutical research. The company is a pioneer in Precision Medicine and the global leader in collaborations with pharmaceutical and biotechnology companies to co-develop companion diagnostics, which detect clinically relevant genetic abnormalities to provide insights that guide clinical decision-making in diseases such as cancer.

Its sample technologies isolate and process DNA, RNA and proteins from blood, tissue and other materials. Assay technologies make these biomolecules visible and ready for analysis. Bioinformatics software and knowledge bases interpret data to report relevant, actionable insights. Automation solutions tie these together in seamless and cost-effective workflows.

Founded in 1984 by Metin Colpan, Karsten Henco, Jürgen Schumacher, the company now employs more than 5,900 people in over 35 locations worldwide. QIAGEN serves more than 500,000 customers around the globe.

This year, QIAGEN received emergency use authorization from the FDA for its QIAreach® SARS CoV-2 Antigen Test, which is designed for environments that require a high volume of fast and accurate test results.

48. Carestream HealthCategory: Medical Devices

Carestream Health is a worldwide imaging company. The company provides digital X-ray products and X-ray film for the medical and non-destructive testing market worldwide. It also provides product, technical, and service support, including remote equipment and software management services. Today, Carestream owns over 600 patents in digital imaging, film, and imaging chemistry.

Carestream was established in 2007 when Onex Corporation purchased Eastman Kodak's Health Group. Today, the company employs around 4,500 people who serve a global customer base. Carestream is headquartered in Rochester, New York, with locations around the world, including Shanghai, Hong Kong and Mumbai.

This year, the company announced it had begun investigating the use of NVIDIA Clara AGX — an embedded AI platform for medical devices — in the development of AI-powered features on single-frame and streaming x-ray applications. Carestream is creating smart X-ray rooms that will include AI-powered features for an enhanced imaging workflow and faster, more efficient exams. The devices include automated positioning and exposure settings for similar exam types, which helps improve the consistency of X-ray images, boosting diagnostic confidence.

49. MeditechCategory: Healthcare Software

Meditech empowers healthcare organizations to keep their patients and their business healthy. The company has driven EHR innovation during every stage of the industry's evolution. Today it helps healthcare organizations around the world with MEDITECH Expanse, a web-based EHR that's setting new standards for usability, efficiency, and clinician satisfaction. Its software is used in almost every healthcare setting, from acute centers and ambulatory practices, to home health and hospice, long-term care facilities, patients’ homes and beyond.

Headquartered in Westwood, Massachusetts, the company was founded in 1969 when co-founder Neil Pappalardo began development of the programming language MIIS. This was one of several proprietary implementations of MUMPS, a programming language which at the time had not been standardized. In that same year, Pappalardo and Morton E. Ruderman, Curtis W. Marble, Jerome H. Grossman and Edward B. Roberts founded the company.

Today, Meditech's software is used by a quarter of all hospitals in the U.S., nearly half of all Canadian hospitals, and healthcare organizations in 23 countries. More recently, Meditech launched Expanse Patient Care, a web-based application software that allows nurses and therapists to conduct administrative tasks through a mobile device.

50. OmnicellCategory: Healthcare Software

Omnicell is a leading provider of automated and business information solutions enabling hospitals and healthcare. The company is focused on transforming the pharmacy care delivery model to dramatically improve outcomes and lower costs.

Over 6,000 facilities worldwide use Omnicell automation and analytics solutions to help increase operational efficiency, reduce medication errors, deliver actionable intelligence, and improve patient safety. More than 40,000 institutional and retail pharmacies across North America and the United Kingdom use Omnicell's innovative medication adherence and population health solutions to improve patient engagement and adherence to prescriptions, helping to reduce costly hospital readmissions.

Omnicell was founded in 1992 by Randall A. Lipps after his daughter was hospitalized at birth and he observed nurses had difficulty locating medical supplies. With the help of graduate students from Stanford University, he developed a prototype of a system that automated inventory management tasks performed manually by nurses. Recently, the company announced it is set to acquire pharmacy software solutions provider, FDS Amplicare for $177 million.

51. MedidataCategory: Healthcare Software

Medidata Solutions offers SaaS-based clinical development solutions addressing the functioning of customers' clinical trials. The company helps generate the evidence and insights to help pharmaceutical, biotech, medical device and diagnostics companies, and academic researchers accelerate value, minimize risk, and optimize outcomes. Medidata and contract research organizations exist to connect pharmaceutical companies with the doctors and nurses who run the trials on the ground.

Founded in 1999, Medidata is headquartered in New York City and has offices around the world, including Boston, Houston, San Francisco, Beijing, Tokyo, London and Singapore. It made its initial public offering on the Nasdaq Stock Market in 2009. And in 2019, Medidata was acquired by Dassault Systèmes. Today, more than one million registered users spanning customers and partners access its platform for clinical development, commercial, and real-world data.

The company has counted Novartis and Tesaro as clients, among other large and small pharmaceutical companies and biotechs. Medidata's cloud platform was used in the clinical trials for Moderna's COVID-19 vaccine.

52. Adamed GroupCategory: Biotech

In 2010, Adamed Group was founded, consisting of: Adamed, Pabianickie Zakłady Farmaceutyczne Polfa and Adamed Consumer Healthcare among others. Adamed Pharma is a pharmaceutical and biotechnological company, founded on the basis of its own scientific advances and a patent portfolio. With a dedicated team of over 2200 employees, Adamed engages in the development, licensing, manufacturing, marketing and distribution of pharmaceuticals and consumer health products into Europe, MENA, Australia and the Pacific region - more than 70 countries globally, the references include the most renowned pharma corporations.

As a company established and still run by medical doctors, Adamed has always put patients’ best interests first. ADAMED has a broad portfolio of incrementally modified therapies which include unique fixed-dose combinations and modified-release formulations backed by significant clinical data and references inline or ahead of the international therapy guidelines in such therapeutic areas as cardiology, urology or CNS diseases.

Its two manufacturing plants located in central Poland comprise Adamed's Production and Logistics Centre. Advanced control systems, state-of-the-art technological solutions, and highly qualified staff ensure the top quality of our products as well as contribute to an exceptional level of customer service as an integral part of the value proposition to its partners.

53. ExosCategory: Medical Devices

Exos is a medical device company that develops and commercializes thermoformable external musculoskeletal stabilization systems. Exos offers a thermoformable bracing system, consisting of a waterproof, removable, adjustable and reformable solution for the treatment of fractures and other injuries requiring stabilization. The Exos advanced technology allows a clinician to mold the brace directly to the patient for the best possible fit, comfort and stabilization. The thermoformable material is light-weight, waterproof, can be easily cleaned, and is radiolucent.

Founded in 2007 by Fariborz Boor, the Minnesota startup was later acquired by DJO Global in 2012. Exos casts and splints are made with a proprietary thermoformable plastic – formed over heat – and can be molded right on the patient to ensure a custom fit. Under the partnership between Exos and DJO Global, the California company sells the cast and splints meant for treating upper extremity fractures.

There are currently 15 different Exos braces with a number of new products in development. The current range includes hand based devices for finger and hand injuries, forearm based devices for hand, wrist and forearm injuries, a humeral fracture brace, and a line of pediatric wrist and forearm fracture braces.

54. JAZZ PharmaceuticalsCategory: Biotech

Jazz Pharmaceuticals is a specialty pharmaceutical company that identifies, develops and commercializes innovative treatments for important, underserved markets in neurology and psychiatry. The company also focuses on identifying, developing, and commercializing products for neurology and psychiatry primarily in the United States.

Founded in 2003 and headquartered in Dublin, Ireland, Jazz Pharmaceuticals has a significant corporate presence in Palo Alto, CA, Philadelphia, PA and Oxford, England, with manufacturing facilities in Ireland and Italy. Together, the company is composed of more than 3,100 experts, spanning analysts, specialists, advocates, scientists and professionals all with diverse backgrounds and perspectives.

Recently, Jazz Pharmaceuticals’ Xywav oral solution for the treatment of idiopathic hypersomnia received FDA approval. Analysts predict that the drug is expected to bring in sales of $1.49 billion by 2025 end, with $1.1 billion from narcolepsy and around $300 million from IH. Its other products include Xyrem for the treatment of cataplexy and excessive daytime sleepiness in patients with narcolepsy and Cystadane for the treatment of homocystinuria, an inherited metabolic disease.

55. Inform DiagnosticsCategory: Biotech

Inform Diagnostics (formerly Miraca Life Sciences) provides expert pathology services in the fields of dermatopathology, breast pathology, GI pathology, hematology/oncology pathology, and urologic pathology. The company also offers health IT consulting services, and has helped hundreds of practices with programs such as MIPS and HIPAA compliance.

The company, previously known as Caris Diagnostics, was renamed Miraca Life Sciences in February 2012. In November 2017, Miraca Life Sciences was acquired by Avista Capital Partners and then rebranded as Inform Diagnostics. The company's laboratories are located in Dallas, Boston, Phoenix, and Union, New Jersey. Additionally, a large non-laboratory office is located in Daphne, Alabama, as well as smaller offices and laboratories in other cities.

Today, the company's team of more than 80 distinguished subspecialist pathologists utilizes state-of-the-art laboratories to serve more than 5,500 patients every day. As a leader in anatomic pathology, Inform Diagnostics combines the rigor of an academic medical institution with the innovative spirit of a technology company.

56. AbiomedCategory: Medical Devices

Abiomed is a pioneer and leader in mechanical circulatory support devices. The company has a mission to recover hearts and save lives, with its products being used by heart surgeons. Its products are designed to enable the heart to rest, heal and recover by improving blood flow and/or performing the pumping function of the heart.

Abiomed, (formerly Applied Biomedical Corporation) was founded in Danvers, Massachusetts by David M. Lederman in 1981. In its first year, the company commenced the development of an artificial heart. Lederman partnered with The Texas Heart Institute to develop the AbioCor, a grapefruit-sized electromagnetic device with an internal battery that completely replaces the heart without wires or tubes passing through the skin. Almost 20 years later, in 2001, the AbioCor became the first artificial heart successfully implanted in a patient, where it pumped more than 20 million times.

Over the last year, Abiomed's revenue increased by 53%, breaking it's own records. This quarter's revenue, which totaled $252.6 million (compared to $164.9 million during the same period of the prior fiscal year) was driven by record global patient utilization with COVID recovery. During the height of the pandemic, Abiomed manufactured and supplied its Impella heart pumps to hospitals to support patients on their road to recovery.

57. STEMCELL TechnologiesCategory: Biotech

STEMCELL Technologies offers high-quality cell culture media, cell separation technologies, instruments, accessory products, and educational resources that are used by scientists advancing the stem cell, immunology, cancer, regenerative medicine, microbiology, and cellular therapy fields.

STEMCELL is Canada's largest biotechnology company, with over 1,500 employees and year-on-year growth of approximately 20% for the last 26 years. Based in Vancouver, STEMCELL supports life sciences research around the world with more than 2,500 specialized reagents, tools, and services.

STEMCELL Technologies was launched in 1993 when founder and CEO Dr. Allen Eaves needed a way to meet the increasing demands for his standardized, cost-effective cell culture media for growing hematopoietic stem cells. Since then, STEMCELL has grown into a global biotechnology company, supporting and collaborating with scientists around the world to achieve their research goals. During the pandemic, products made by STEMCELL was used in over 30 COVID-19 studies worldwide.

58. GenmabCategory: Biotech

Genmab is a biotech company specializing in creation and development of differentiated antibody therapeutics for treatment of cancer. The company's discovery, development, and manufacturing teams use innovative technology to create and develop products that address unmet medical needs.

Genmab's four marketed products include, DuoBody for generation of bispecific antibodies, HexaBody, which creates effector-function enhanced antibodies and HexElect, which combines two co-dependently acting HexaBody molecules to introduce selectivity while maximizing therapeutic potency. Meanwhile, DuoHexaBody enhances the potential potency of bispecific antibodies through hexamerization.

Founded in 1999 by Florian Schönharting, Genmab is headquartered in Copenhagen, Denmark with sites in Utrecht, the Netherlands, Princeton, New Jersey, US and Tokyo, Japan. The company completed its initial public offering in 2019, raises $582 million in Europe's largest ever NASDAQ IPO.

This year, Genmab and Bolt Biotherapeutics have teamed up to develop bispecific immune-stimulating antibody conjugates (ISACs). The collaboration brings together Genmab's bispecific capabilities with Bolt's innate immune stimulant platform to create a new type of immuno-oncology drug.

59. HealthStreamCategory: Healthcare Software

HealthStream provides internet-based learning and research solutions to meet the training, information, and education requirements. The company is dedicated to improving patient outcomes through the development of healthcare organizations' greatest asset: their people. Its suite of solutions is contracted by healthcare organizations in the US for workforce development, training and learning management, credentialing, provider enrollment, performance assessment, and managing simulation-based education programs.

HealthStream's patient experience and research solutions provide valuable insight to healthcare providers to meet CAHPS requirements, improve the patient experience, engage their workforce and enhance physician alignment.

HealthStream was founded in 1990 by Robert A. Frist Jr. The Nashville-based company now has offices in Laurel, Maryland; Brentwood, Tennessee; Pensacola, Florida, Jericho, New York, and San Diego, California. HealthStream employs over 1,100 individuals and has contracted its solutions to over 4,000 healthcare organizations across the United States.

This year, HealthStream acquired Chicago-based policy management software firm, ComplyALIGN. This continues the company's acquisition run that last year saw it spend more than $130 million on four deals.

60. HalodocCategory: Consumer HealthTech

Halodoc is a health-tech platform that connects patients with doctors, insurance, labs, and pharmacies in one simple mobile application. HaloDoc connects users to a network of 19,000 licensed doctors, 1,000 certified partner pharmacies through medical delivery service ApotikAntar, and licensed medical laboratory services. Users can communicate with these medical professionals through chat, video and voice calls.

Founded in 2016 by — current CEO — Jonathan Sudharta, the Indonesian health tech startup has grown to become Indonesia's leading health tech provider. Today, Halodoc provides over 20 million users with convenient and reliable healthcare services every month.

Notably, Halodoc has been at the forefront of Indonesia's fight against COVID-19. The technology that powers its appointment system is now being used to provide a safe and efficient patient journey for COVID-19 testing and vaccinations.

This year, the company announced it had raised a funding round for Halodoc's expansion of services and technology-based solutions in Indonesia, where healthcare access remains limited.

61. Carbon HealthCategory: Consumer HealthTech

Carbon Health is a tech-enabled healthcare company that delivers virtual care experience. The company offers primary care services through a mobile app that enables users to follow-up on a treatment plan, manage prescriptions, and see lab reports all in one platform. Patients can also get treated for certain conditions such as poison ivy, cold sores and eczema by messaging Carbon providers in the app. In March, 2020, Carbon Health created a COVID-19 assessment tool to help mitigate the pandemic, and also provided testing in its California clinics.

Carbon Health was founded in 2015 by Caesar Djavaherian, Eren Bali, Greg Burrell and Tom Berry who wanted to create a system built hand-in-hand with doctors and patients that would be intuitively easy-to-use instead of requiring hours of training. The company has grown extensively over the course of the pandemic. In December, it boasted a sixfold increase in patient volume over the course of 2020. It has also expanded to more than 70 clinics across 13 states and launched a COVID-19 workplace safety program for employer customers.

62. Village MDCategory: Consumer HealthTech

VillageMD collaborates with primary care physicians to maximize success in a changing health care environment. VillageMD's goal is to be the largest, highest performing primary care-led network in the U.S. The company is a provider of healthcare for organizations moving toward a primary care-led, high-value clinical model.

The VillageMDsolution provides the tools, technology, operations, and staffing support needed for physicians to drive the highest quality clinical results across a population. VillageMD works with physician groups, independent practice associations, and health systems to improve quality, deliver a first-rate patient experience, and lower costs in the communities they serve.

In 2013, its three founders — Clive Fields, Paul Martino, Tim Barry — came together with a passion to fundamentally change the trajectory of healthcare by leveraging a clinical model that would anchor around primary care physicians, giving them the tools and resources needed to fulfill their Hippocratic oath to care for patients to the best of their ability.

Now the Walgreens-backed company is said to be considering an initial public offering, which would make it the latest primary care provider to become publicly-traded to boost its expansion efforts.

63. Lyra HealthCategory: Consumer HealthTech

Lyra Health helps companies improve access to effective, high-quality mental health care for their employees. Lyra's matching technology and innovative digital platform connects members to a curated network of top therapists and coaches, which triples the amount of people receiving care and increases the chance of better outcomes than traditional plans and EAPs seven-fold.

The startup uses a "blended care" program, which pairs therapy sessions with online lessons and exercises. It recommends providers based on patients’ schedule and preferences. The company also offers health coaches for people who need short-term support, and has stuck partnerships with other digital health tools like MyStrength and meditation app Calm.

Lyra was founded in 2015, by Bob Kocher, David Ebersman, and Dena Bravata. Today, the Burlingame, California-based company works with 72 employers representing roughly 2 million members. Some of its customers include Genentech, Morgan Stanley and Starbucks.

In 2020, it saw the number of clients double as companies sought to build out their mental health benefits in response to the COVID-19 pandemic. Earlier this year, Lyra raised $187 million in funding, giving it a valuation of $2.3 billion.

64. Flatiron HealthCategory: Consumer HealthTech

Flatiron Health is a healthcare technology company focused on accelerating cancer research and improving patient care. The company's platform enables cancer researchers and care providers to learn from the experience of every patient. Its database platform aggregates and transforms clinical and financial data from electronic medical records (EMRs) and billing systems that provide comprehensive support to the cancer care providers and life science companies.

Founded in 2012 by Nat Turner and Zach Weinberg, the New York-based company has grown immensely since, now partnering with over 280 community cancer practices, seven major academic research centers, and over 15 of the top therapeutic oncology companies.

Recently, the company announced its data supports the FDA approval of a new dosing regimen for ERBITUX® (Eli Lilly and Company's cetuximab) that can have a direct positive impact on the lives of patients with metastatic colorectal cancer (CRC) or squamous cell carcinoma of the head and neck (SCCHN). This will significantly reduce the frequency of patient visits to an infusion center.

65. Taconic BiosciencesCategory: Biotech

Taconic Biosciences is a fully-licensed, global leader in genetically engineered rodent models and services. Founded in 1952, Taconic provides the best animal solutions so that customers can acquire, custom generate, breed, precondition, test, and distribute valuable research models worldwide.

Specialists in genetically engineered mouse and rat models, precision research mouse models, and integrated model design and breeding services, Taconic operates three service laboratories and six breeding facilities in the U.S. and Europe, maintains distributor relationships in Asia and has global shipping capabilities to provide animal models almost anywhere in the world.

This year, the company announced the launch of a new COVID-19 mouse model. This human ACE2 (hACE2) transgenic mouse expands Taconic's COVID-19 research toolkit. In October 2020, Taconic launched its first hACE2 model. The AC70 mouse experiences a lethal response to infection by SARS-CoV-2, the virus that causes COVID-19. Conversely, the new AC22 mouse is lethality-resistant, enabling therapeutic, vaccine, and post-infection symptom research.

66. TelstarCategory: Biotech

In life sciences fields requiring design and manufacturing of equipment solutions with high demands on technological complexity, Telstar has consolidated its position as a leader in applications in the pharmaceutical, cosmetic and biotechnology industries, backed by 50 years’ experience and a strong international presence.

Telstar has a long track record and experience in the development of engineering and construction projects, process equipment and GMP services solutions, including turnkey projects and critical installations, for companies associated with Life and Health Sciences (pharmaceutical and biotechnology, healthcare, cosmetic, veterinary and food and beverage industries, hospitals, laboratories and research centers). Under the Telstar brand, the company also offers solutions for Vacuum and High-Vacuum technologies for conventional industry and high-tech industry in the power and aerospace sectors, as well as for major scientific experiments.

67. CertaraCategory: Biotech

Certara accelerates medicines using biosimulation software and technology to transform traditional drug discovery and development. Its clients include more than 1,650 global biopharmaceutical companies, leading academic institutions, and key regulatory agencies across 61 countries. The company anticipates and addresses critical drug discovery and development risks and decisions.

As your trusted partner, Certara supports confident decision-making throughout the entire biopharma R&D process to reduce cycle times, lower costs, and improve outcomes for patients.

Additionally, 17 global regulatory agencies have adopted Certara's Phoenix™ PK/PD and/or Simcyp™ PBPK Simulator software platforms, including the US FDA and EMA. The company's customers, who use its biosimulation software and services, have received over 90% of all new drug approvals by the FDA since 2014.

68. XACT RoboticsCategory: Medical Devices

XACT Robotics is a privately held company focused on advancing the field of radiology by launching the world's first and only hands free robotic solutions that can significantly improve targeting accuracy, efficiency and consistency in percutaneous radiology procedures.

XACT Robotics’ proprietary robotic system, XACT ACE, was cleared by the FDA in July 2020. The system combines image-based procedure planning and monitoring with robotic instrument insertion and non-linear steering capabilities, to meet the growing demand for percutaneous procedures with benefits to both the patients and the radiology team.

The robot is able to accurately and consistently reach very small targets of interest in the body, typically on the first insertion, during procedures such as ablations, biopsies and targeted drug delivery.

The company was founded in 2013 by Harel Gadot, a renowned entrepreneur in the MedTech robotics space. Since then, the company has grown to employ over 60 leaders in the robotics and medical technology space. To date, the XACT ACE system has been adopted by multiple radiology departments at leading hospitals in the US, including Lahey Hospital & Medical Center (LHMC) in Massachusetts and Sarasota Interventional Radiology in Florida.

69. Alto PharmacyCategory: Consumer HealthTech

Alto Pharmacy is an on-demand pharmacy that offers patients free same-day prescription delivery, cost transparency, and pharmacist access. The company is motivated to transform pharmaceuticals — a $500 billion industry — by reinventing what pharmacies can do. Alto is currently available in New York City, San Francisco, Bay Area, Los Angeles, Orange County, the Denver-Boulder Metro Area, Las Vegas, Seattle, Houston, Dallas, Sacramento, and Santa Barbara.

Alto Pharmacy was started in 2015 by two Facebook engineers, Jamie Karraker and Mattieu Gamache-Asselin, who were frustrated with the existing pharmacy experience, how bad it was and especially how little technology was being used within these systems. The San Francisco, California-based company began in a storage closet and has since grown to open eight offices across the US, including locations in New York City, Las Vegas and Denver.

This year, the patient-centric telehealth pharmacy announced that it's set to launch its full-service telehealth pharmacy services in San Diego, California and Austin, Texas this fall. The addition of these two new markets brings Alto's total coverage area to more than 41 million people across ten major metropolitan areas.

70. CapsuleCategory: Consumer HealthTech

Capsule is a modern way for people to get their prescriptions. The company has completely digitized the pharmacy experience by offering a sleek platform, efficient software, and making prescriptions easier than ever to get filled. Consumers have the ability to chat or text with their pharmacist about any questions they have, whether it's about their medications or insurance. They can also schedule free same-day, two-hour delivery, anywhere in New York City. And then Capsule takes the reins to keep the conversation going with doctors to ensure people never run out of their medication.

Capsule was founded in 2016 by Eric Kinariwala, who was determined to inject humanity into the pharmacy experience, and essentially rebuild the $425 billion pharmacy industry from the inside out. A former analyst at Bain Capital and Perry Capital, Kinariwala launched the New York-based company, after he had had trouble picking up sinus medication from his local pharmacy.

Today, Capsule has raised over $500 million from the best healthcare and technology investors in the world. Most recently, the company raised $300 million in a Series D funding round in April this year, which it hopes to use to expand to new markets and invest in its technology.

71. AdvancedMDCategory: Healthcare Software

AdvancedMD is a healthcare technology company that offers cloud medical office software to ambulatory medical practices. The company supports independent physicians and their staff with a comprehensive suite of solutions including practice management, electronic health records, telemedicine, patient relationship management, and business analytics reporting. AdvancedMD offers a flexible outsourced billing option for practices looking to use a third-party billing company.

Founded in 1999, the South Jordan, Utah-based company serves more than 37,000 practitioners across 13,000 practices and 700 medical billing companies. The company claims that it processes over 6.5 million insurance claims every month on the AdvancedMD billing platform.

AdvancedMD is considered one of the best electronic medical record (EMR) and practice management software (PMS) solutions, because it seamlessly combines a comprehensive clinical platform with effective practice management software and a billing solution at a competitive cost. It's also built to grow with medical practice, making it a flexible solution and cost-effective solution. With AdvancedMD medical practices are able to manage higher patient volumes with improved productivity and financial outcomes. Patients are able to electronically connect and engage with their providers and healthcare experience.

72. EverlyWellCategory: Consumer HealthTech

EverlyWell is a digital health company that offers consumer testing, virtual care, at-home collection tests, and digital results. The company connects people to certified labs which offer a suite of validated lab tests including tests for cholesterol, heart health, fertility, STIs, Lyme disease and more. Everlywell also offers FDA-authorized at-home sample collection test kits for COVID-19, and was the first to provide access to at-home sample collection lab tests for fertility, high-risk HPV, and indoor and outdoor allergies.

EverlyWell was founded by Julia Taylor Cheek in 2015, who left her corporate job at MoneyGram International to pursue creating this company. The idea was borne out of a personal experience that led to her racking up thousands of dollars in lab tests. So Cheek set out to find a way to make lab tests affordable.

Today, the Austin-based home lab testing kit startup is expanding, and has established its new parent company — led by Cheek — called Everly Health after it acquired PWNHealth and Home Access Health. PWNHealth will rebrand to Everly Health Solutions, and offer health plans, employers and labs across the US.

73. Unite UsCategory: Consumer HealthTech

Unite Us provides collaboration and coordination software, streamlining the delivery of health and social services. The company helps systems and communities efficiently deliver care and services by inter-connecting providers across communities, seamlessly integrating the social determinants of health into patient care.Providers across the continuum and community are able to externally refer and track every patient's total health journey while reporting on all tangible outcomes across a full range of services in a centralized, cohesive, and collaborative ecosystem. This social infrastructure helps communities move beyond legacy resource directories, and transform their ability to measure impact, improved health, and outcomes at scale.

The New York City-based company launched in 2013 with a software platform to help connect people to social services. As it scales up a nationwide social care network, the startup has attracted backing from major healthcare and tech investors including Salesforce and Town Hall Ventures, led by former Centers for Medicare & Medicaid Services Administrator Andy Slavitt.

This year, Unite Us raised its largest funding round to date, closing $150 million in series C financing led by Iconiq Growth. The round was backed by Optum, Emerson Collective, Transformation Capital, Define Ventures and several healthcare partners as well as existing investors Salesforce and Town Hall.

74. CMR SurgicalCategory: Medical Devices

CMR Surgical is the UK's leading surgical robotics company, developing the next-generation surgical robotic system for minimal access surgery. CMR works with surgeons and hospitals to provide an optimal tool to make robotic keyhole surgery universally accessible and affordable. In 2018, the company launched Versius, its next-generation robotic system that has been successfully launched in multiple locations worldwide including across Europe, Australia, India and the Middle East.

CMR Surgical, formerly known as Cambridge Medical Robotics was founded in 2014 by Luke Hares, Mark Slack and Martin Frost. Today the company has 582 employees across 2 locations.

This year, the SoftBank-backed start-up began to show interest in establishing a presence in Hong Kong as it looks to expand into mainland China and the Asia-Pacific for its surgical robotic system, Versius. The minimally invasive system is responsible for around 1,000 successful surgeries worldwide so far and, with the help of this new capital, will spread to more hospitals worldwide.

75. Surgical Information SystemsCategory: Healthcare Software

Since 1996, Surgical Information Systems has been dedicated to providing surgical care providers with the solutions and services they need to deliver improved operational, financial, and clinical outcomes. Focused exclusively on perioperative IT, SIS serves over 2900 facilities across the United States and Canada.

SIS provides business office management, clinical documentation, and patient communications tools that meet the unique needs of ASCs. SIS is a leading provider of anesthesia information management systems (AIMS) and perioperative solutions to hospitals and outpatient surgery departments.

The SIS product suite is built specifically for the perioperative environment and includes hospital and ASC-focused solutions covering perioperative Electronic Medical Records (EMRs), Anesthesia Information Management Systems (AIMS), ASC business management, and business intelligence and analytics solutions. SIS AmkaiCharts solution is the No. 1 ranked outpatient EMR. Services, including revenue cycle management and ASC advisory services, complement SIS’ software solutions.

76. Atos MedicalCategory: Medical Devices

Atos Medical is a medical device company that focuses on voice and pulmonary rehabilitation of patients who have undergone a Laryngectomy, the surgical removal of their voice box. Today, the company serves the needs of more than 100,000 people with neck stomas around the world. Determined to remain at the forefront of first-rate product development, Atos prioritizes clinical research and education of both professionals and patients as integral parts of our business.

Founded in 1986 by Swedish entrepreneurs Gert and Jan-Ove Persson, Atos Medical was born out of a desire to make life easier for people living with a neck stoma. Since the introduction of the first Provox® voice prosthesis in 1990, Atos Medical has become the world leader in laryngectomy care. Today, its products are featured in over 150 peer-reviewed publications and we support and conduct hundreds of conferences and educational programs every year.

French private equity firm PAI, bought the laryngectomy care products supplier in 2016 for 900 million euros from buyout fund EQT and has since strengthened the company through a string of acquisitions including Griffin Labs and Heimomed Heinze. Now, the Swedish voice prosthesis group is preparing for an IPO, with an expected valuation of around $2.4 billion.

77. TelcorCategory: Healthcare Software

Founded in 1995, Telcor is an innovative company providing healthcare software and service solutions to more than 2,600 hospitals and laboratories across the United States and Canada. The company values and prioritizes integrity and teamwork, which makes it able to respond quickly to any industry or technology changes keeping it at the forefront of innovation.

Its software, Telcor RCM, and its billing service, Telcor Revenue Cycle Services, enables laboratories to control their revenue cycles and billing functions. Meanwhile, its lab-specific solutions give labs unparalleled visibility to manage its revenue ensuring collections are increased and operating costs are minimized.

Telcor is the go-to choice across the country to manage rapidly expanding POC programs, as Telcor QML is one of the most comprehensive POC data management and connectivity systems on the market. QML provides workflow efficiency, scalability and compliance as hospital POC programs encompass new device types and ambulatory facilities.

78. Aspen SurgicalCategory: Medical Devices

Aspen Surgical is a worldwide manufacturer of medical disposable products that focuses on efficiency and safety in the hospital and surgical markets. The company's extensive portfolio includes Bard-Parker blades and scalpels, Precept personal protective equipment, Protek probe covers and needle guides, surgical marking pens, orthopedic positioners, and Stork obstetric products as well as basic wound care products.

Established in 1999, Aspen Surgical was founded by entrepreneur Daniel Bowen and later sold the company to Lake Forest, Illinois-based RoundTable Healthcare Partners in 2006. Hill-Rom originally purchased Aspen Surgical for $400 million in July 2012. Today, the Caledonia, Michigan-based company has facilities located in Michigan, Puerto Rico and Mexico.

This year, Aspen has acquired Stork, which offers line of products including high-quality, branded sterile disposable obstetric products, such as the Plastibell Disposable Circumcision Device and the Amnihook Amniotic Membrane Perforator. The acquisition of Stork strengthens Aspen's broad portfolio of medical and surgical disposables sold into the acute care market. Aspen also acquired BlueMed Medical Supplies, a manufacturer of high-quality, cost-effective disposable shoe covers and other personal protection products based in Montreal, Canada.

79. Parsley HealthCategory: Consumer HealthTech

Parsley Health is a new kind of healthcare service that integrates technology, nutrition, wellness and prevention into cutting-edge primary care. The company is a healthcare membership, where customers are offered a holistic approach to their health by a team of doctors and health coaches, complete with 24/7 unlimited messaging. Parsley members spend around four hours/year with medical professionals, including five doctor visits a year and five health coach visits.

The company was founded in 2016 by Dr. Robin Berzin, M.D, a Columbia-trained physician, digital health expert and leader in functional medicine. Today, Parsley has clinics open in Los Angeles, NewYork City and San Francisco. Parsley Health experienced rapid expansion in 2020 has brought it to more than 47 states across the country and has grown membership by more than 20x since February.

80. KindbodyCategory: Consumer HealthTech

Kindbody serves as a one-stop shop of family-building options, offering everything from egg freezing and IVF, to gynecological care for patients. Kindbody's first clinic launched in August of 2018 in New York City, and it has since added clinics in San Francisco and Los Angeles and today the company has more than 300 in-person clinics all over the country.

The company was founded by Joanne Schneider and Gina Bartasi, the founder and former CEO at Progyny, a provider of accessibility to doctors, price transparency, and financing. That company went public in October and is now valued at $2.3 billion. Kindbody has raised a total of $125 million in funding from investors, including a $62 million Series C round in June, the largest amount raised by a fertility company in history.

This year, Kindbody announced the launch of Kindbody360, a dynamic and integrative solution focused on holistic care. Kindbody360 deftly augments Kindbody's fertility and family-building offering with mental, physical, and emotional support from pre to postpartum, in-clinic, online and via its telehealth platform.

81. CentivoCategory: Consumer HealthTech

Centivo offers a digital health plan aimed at self-funded employers looking to provide employees with quality care they can afford. An alternative to traditional insurance carriers or third-party administrators, Centivo offers the technology, network, claims processing, customer support, and population health management to fully administer health benefits for all or a portion of an employee population. The Centivo model emphasizes the partnership between individuals and their primary care team as the proper model to coordinate healthcare needs.

Centivo was founded in 2017 by Alan Cohen, Ashok Subramanian, Boris Khomut, Jordan Silvergleid, Ruth Berkowitz, Stuart Roth, and Tahasin Alam. The goal was to bring cost sustainability to employers and affordable healthcare to the millions of Americans who struggle to pay their healthcare bills. Today, Centivo is available in Florida, New Jersey, Connecticut, New York, North Carolina, and Southern California. In 2022, Centivo is launching networks in Iowa and northeastern states including Wisconsin.

Centivo has raised a total of $70 million in funding over three rounds and is backed by Bain Capital Ventures, F-Prime Capital Partners, Maverick Ventures, Bessemer Venture Partners, Ingleside Investors, Rand Capital and more.

82. TytocareCategory: Consumer HealthTech

​​TytoCare is the maker of an all-in-one device for remote medical exams. While traditional telehealth relies on smartphone cameras or webcams, the TytoCare device enables users to perform comprehensive self-examinations with the remote help of a doctor in its network.

The company seamlessly connects people to clinicians to provide the best remote home care. TytoCare has three telehealth products: TytoHome for consumers, TytoPro for professionals, and TytoClinic for remote point-of-care locations. All solutions are designed to replicate a face-to-face clinician visit and include a hand-held modular examination tool for examining the heart, lungs, skin, throat, ears and body temperature; a complete telehealth platform for sharing exam data, conducting live video exams and scheduling visits.

Dedi Gilad and Ofer Tzadik and industry experts founded ​​TytoCare in 2012. TytoCare has received funding from OrbiMed, Walgreens, Fosun Pharma, LionBird, Teuza VC and others. The TytoCare device comes with several attachments, including an otoscope for examining the ears, an FDA-approved stethoscope, and a tongue depressor. The Israel-based company says it enabled 650,000 telehealth visits worldwide in 2020, many through partnerships with insurers and hospital networks.

83. Cricket HealthCategory: Consumer HealthTech

Cricket Health is a specialty kidney care provider of integrated nephrology and dialysis care for people with chronic kidney disease (CKD) and end stage renal disease (ESRD). Through its StageSmart™ predictive analytics model, Cricket Health is able to identify patients with chronic kidney disease with 96% accuracy. The company extends care delivery capabilities through the MyCricket patient support service, which includes a multidisciplinary care team, peer support, and educational resources available any time virtually, as well as by telephone or in person when needed.

Founded in 2015 by Arvind Rajan, Brian Guarraci, James Chaukos, and Vince Kim, the Boston, Massachusetts-based firm's leadership includes some of the leading experts in nephrology, health care, and technology. Today, the company has 136 employees across four locations, including San Francisco, Cambridge, and Burlingame.

This year, Cricket raised $83.5 million in a Series B funding round, bringing its total funds raised to well over $100 million. The company plans to use this most recent injection of funds to rapidly expand its support model to care for people with kidney disease across the United States.

84. BioLife SolutionsCategory: Medical Devices

BioLife Solutions is a class-defining cell and gene therapy bioproduction tools and services company. Its solutions give life science companies and clinical researchers significant improvement in shelf life, post-preservation viability and function of biological materials.

BioLife Solutions is a leading supplier of cell and gene therapy bioproduction products and services. Our portfolio includes our proprietary CryoStor freeze media and HypoThermosol shipping and storage media, ThawSTAR family of automated, water-free thawing products, evo cold chain management system, Custom Biogenic Systems high-capacity cryogenic freezers, Stirling Ultracold ULT freezers, and SciSafe biologic materials storage.

Founded in 1987 by Aby Mathew, the Bothell, Washington-based company was incorporated in 1998 and listed on the NASDAQ under the symbol BLFS. Today, the company employs more than 400 dedicated team members across two office locations.

This year, BioLife Solutions acquired Sexton Biotechnologies. Sextion's portfolio includes portfolio includes proprietary closed vials for cell therapy final dose packaging, human platelet lysate (HPL) media, a bio-defined replacement for fetal bovine serum or human serum used in cell manufacturing, and automated cell processing machines.

85. eVisit IncCategory: Healthcare Software

eVisit is a SaaS telehealth company focused on enabling virtual care for hospitals and health systems. Its leading virtual care platform enables healthcare organizations to improve outcomes, revenue, and efficiencies—using their own network of providers to deliver virtual care. With eVisit, healthcare organizations deliver faster, more convenient care to their patients with virtual urgent care, primary care, specialty care, pre-post op care, and employee care.

Some of the largest healthcare systems in the US use eVisit as its telemedicine provider, including Scottsdale-based HonorHealth, Chicago-based Blue Cross Blue Shield and Altamonte Springs, Florida-based Adventist Health System. Smaller clinics also use eVisit to implement telemedicine offerings.

The company was founded in 2013 by Bret Larsen, Deric Frost, Glen McCracken, and Miles Romney, all of whom wanted to do something "that could change the world." eVisit has grown exponentially through the pandemic as healthcare providers looked to find efficient ways to provide virtual care.

This year, eVisit continues to expand with an update to its eVisit Enterprise platform, which now includes the Spanish language, extended Single Sign On (SSO) support, reduction in clicks-to-visit, and automated approaches for the secure delivery of eVisit data.

86. RubiconMDCategory: Healthcare Software

RubiconMD advances its mission to democratize medical expertise by connecting primary care clinicians to top specialists. Through its digital platform, RubiconMD enables the remote exchange of insights between clinicians that eliminates unnecessary referrals and services, reduces patient wait time and travel burdens, and allows primary care to practice at the top of their license.

The company was founded in 2013 by Carlos Reines, Gil Addo, and Julien Pham with a vision of democratizing medical expertise so that providers can offer every patient the care they deserve. Today, RubiconMD is furthering this mission with the industry-leading eConsult platform, supported by a best-in-class specialist panel, strategic partnerships, top investors and a smart, passionate team.

This year, RubiconMD launched a suite of COVID-19 vaccine resources to continue supporting primary care physicians throughout the pandemic. Clinicians will be able to submit eConsults to RubiconMD's panel of COVID-19 vaccine experts, review real eConsult case studies submitted on the platform, and leverage a range of educational resources curated in partnership with CONVINCE USA Initiative at the CUNY Graduate School of Public Health and Health Policy.

87. AbbotCategory: Medical Devices

Abbott is a global healthcare leader that has a portfolio of healthcare technologies that runs the gamut from diagnostics and medical devices to nutrition and branded generic medicines. Its product portfolio includes Norvir, a treatment for HIV; Synthroid, a synthetic thyroid hormone; Depakote, an anticonvulsant drug; and Humira, a drug for rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis. Notably, Abbott scientists pioneered the development of the first HIV blood screening test in 1985.

Founded in 1944 by Chicago physician Wallace Calvin Abbott, the Illinois City-based company has over 109,000 employees and serves people in more than 160 countries. Since its inception, Abbott has grown to also operate a product manufacturing segment known as Abbott Point-of-Care. This sector creates diagnostic products for blood analysis and provides cardiac assays to emergency rooms.

President and CEO, Robert Ford led Abbott through 2020 and oversaw its return to pre-pandemic sales levels. In July, the company announced that its second quarter profits doubled due to its sales of COVID-19 tests. Abbott's net income jumped to nearly $1.2 billion, in the second quarter ending June 30, 2021, compared to $537 million, in the second quarter of 2020.

88. ExplORer SurgicalCategory: Healthcare Software

Explorer Surgical is dedicated to innovating and developing scalable digital technologies to put best practices in the hands of all procedural teams. The company offers an interactive surgical playbook that reduces disruptions and wasted disposables by improving surgical team communication. It also provides real-time performance and scheduling data to operating room administrators to enhance the quality of care and efficiency. Surgical teams use the software to coordinate their activities while managing their tools and supplies, resulting in optimal teamwork, increased efficiency, and high performance.

Founded in 2015, Explorer Surgical started as a research project at the University of Chicago Medical Center in the Department of Surgery by Jennifer Fried and Dr. Alex Langerman. Dr. Langerman is a speaker and author on surgical ethics, video and data recording in the operating room, operating room efficiency, and clinical care of head and neck cancer patients.

89. Good Clean LoveCategory: Consumer HealthTech

Good Clean Love is a woman-owned company that provides vaginal care and intimacy products formulated without petrochemicals, parabens and other ingredients that damage vaginal tissue and increase the risk of vaginal infection.

The company was established in Eugene, Oregon in 2003 by Founder and Chief Executive Officer Wendy Strgar. Strgar started the company in her kitchen after hearing many stories about — and experiencing for herself — the painful side effects of using petrochemical-based hygiene and intimacy products.

Today, the company continues to revolutionize intimacy and feminine hygiene products using its patented Bio-Match technology. Good Clean Love was named among the safest lubricants on the market in a National Institutes of Health (NIH) study 2 and has proudly donated over 1 million product samples to physicians and medical facilities worldwide.

The company grew more than 40% in 2020 and tripled its direct-to-consumer business. Good Clean Love products can be found on more than 50,000 retail shelves at key retailers including Target, CVS, Walgreens, Kroger, Whole Foods Market and more.

90. Tivic HealthCategory: Consumer HealthTech

Founded in 2016 and based in Silicon Valley, Tivic Health is a commercial phase bioelectronic health company that develops microcurrent devices to treat chronic diseases. The company's first product, ClearUP, is the only FDA cleared device that uses microcurrent to relieve sinus pain and congestion.

Earlier this year, the FDA expanded the use of ClearUP which created an area of technology never previously granted by the FDA: the use of microcurrent for congestion relief. TivicHealth's mission is to provide individuals suffering from chronic conditions new ways to improve their quality of life through the use of non-pharmaceutical, bioelectronic solutions. The company's non-invasive approach to bioelectronic medicine allows for faster innovation, accelerated time to market, improved safety profiles and broader market penetration.

Looking toward the future, Tivic Health believes its microcurrent bio-electronic technology can be applied to address other conditions with large patient populations and unmet treatment needs. ClearUP is available online at Amazon, Best Buy, FSA/HSA stores, QVC, Sharper Image, Walgreens and Walmart and has received numerous awards.

91. KinnosCategory: Biotech

Kinnos is a biotechnology company pioneering color technology to revolutionize how people use disinfectants. The company's first product, Highlight, is a point-of-use additive that greatly improves visibility and end-user compliance of disinfectants. Their goal is to empower people to disinfect surfaces with confidence and to provide society with peace of mind through disinfection they can see. Its second product, Highlight wipes, is designed for hospitals in the US.

The solution is pretty simple, with Kinnos products including additives that cause disinfectants to turn blue long enough to ensure a surface has actually been covered. The New York startup was founded by Jason Kang, Katherine Jin and Kevin Tyan in 2014. Notably, Kang, Jin and Tyan started the company while still students at Columbia University. Kinnos’ product was developed to target epidemic outbreaks, with the trio formulating the idea in 2014 during the height of the Ebola outbreak in West Africa.

During the height of the pandemic, Kinnos sold to humanitarian organizations that deployed the product in Liberia and Guinea, Haiti, DR Congo and Uganda, and also had a number of shipments go to China for the ongoing COVID-19 outbreak.

92. Vizzia TechnologiesCategory: Healthcare Software

Vizzia Technologies is a software and managed service provider of real-time location systems (RTLS) and advanced process improvement solutions for healthcare organizations. Its award- winning software platform provides real-time, actionable data and process visibility to improve enterprise efficiencies and patient care for leading health systems, hospitals, and clinics.

Founded 2005 in Atlanta, Georgia, the company has established the Vizzia IoT Lab at the University of New Mexico (UNM) School of Engineering in Albuquerque, New Mexico. Its services are installed in over 150 hospitals and clinics across the US. The company's solutions include: asset management, contact tracing, environmental monitoring, hand hygiene compliance, hospital wayfinding, and patient workflow. Vizzia's technology partners include: CenTrak, Sonitor Technologies Cooper/Signify and Phunware.

This year, Phunware, a fully-integrated enterprise cloud platform for mobile that provides products, solutions, data and services has partnered with Vizzia to offer its digital front door solution on mobile to leading healthcare organizations that use Vizzia's real-time location systems (RTLS) technology. This end-to-end, holistic approach eliminates the pain of having to manage dozens of point solutions, while simultaneously offering staff, patients and visitors a far more simplistic, cohesive and integrated healthcare experience.

93. Neopharma Technologies LtdCategory: Medical Devices

Neopharma Technologies Limited is an Australian public company that specializes in the development of innovative and unique medical devices. The company's Tamper Loks Data Vault drug testing solution is a unique tamper-proof drug of abuse specimen collection and testing device that comprehensively address issues relating to adulteration, substitution and other forms of tampering in the enforcement of drug screening. TamperLoks effectively addresses the concerns of transparency, corruption, chain of custody and other legal and practical issues within the exercise of drug abuse enforcement.

Neopharma Technologies drug testing solution aims to become the gold standard for drug testing globally. Founded in 2017, the company has gone on to create an advanced cloud-based platform to accompany its drug testing solution. The DataVault technology is a fully encrypted cloud-based Enterprise Resource Management platform providing security and reliability of test data including collection, transfer, storage, management, administration, and reporting. DataVault can be easily configured to the workflow of individual client's needs offering flexibility and control of their data and chain-of-custody.

94. Neuro42Category: Medical Devices

Neuro42 is a medical technology company focused on diagnostic imaging and image guided surgical interventions of the brain. The company is developing and commercializing an intraoperative MRI and robot that allows easy access to screening, diagnosis and interventions of neurological diseases.

One of the most significant advantages Neuro42's technology brings to the market is that its novel scanner allows for robotic procedures outside of the traditional magnetic resonance suite, expanding the possibilities of intraoperative image guidance and disease treatment. The San Francisco, California-based company was founded in 2020 by a team of successful entrepreneurs and healthcare innovators. Today, Neuro42's platform — which is backed by over 30 patents — is poised to enhance patient and physician experience with its novel, easy-to-use and portable configuration.

This year, the company announced the close of a financing round led by Zepp Health. The financing will enable Neuro42 to advance the development of the first-of-its-kind MRI and robot, and allow physicians to diagnose brain injury in acute settings and treat neurological diseases intraoperatively under live imaging.

96. Dakota SoftwareCategory: Healthcare Software

Dakota Software provides regulatory compliance solutions, including software, content, and consulting to the world's leading organizations to manage risk and improve environmental, health, and safety performance. Notably, Dakota Software was the first company to release EHS compliance software, which was originally designed to automate the environmental auditing process. Today, Dakota is dedicated to delivering the crucial information that helps their users reign in the chaos of EHS compliance.

Founded in 1988, the Cleveland, Ohio-based company has been the go-to software for EHS professionals for over 25 years. In 2017, Dakota improved its offerings with the introduction of its ProActivity Suite. This suite helps users determine which regulatory requirements are applicable to them and guides them in the creation of unique compliance profiles. It prompts continued compliance by automatically notifying users of forthcoming requirements and recent regulatory changes.

Today, ​​Dakota participates in countless community and technology events including programs that further student education in science, technology, engineering and math (STEM) programs at the high school and university level.

97. PaceMateCategory: Medical Devices

PaceMate, the leading digital healthcare company in compliant cardiac data management. PaceMate's fully automated, bidirectional EHR-integrated platform—PaceMateLIVE—is a comprehensive, cloud-native cardiac data management solution, delivering round-the-clock remote monitoring service, customized alerts and automated billing codes.

The PaceMate team developed innovative technology to streamline the device clinic, improve workflow, reduce medical errors and take better care of patients. Today, PaceMateLIVE is a best-in-class, cloud-native software+service solution for real-time cardiac device management—supporting clinics 24/7, 365 days a year. Device-generated data automatically uploads to our vendor-neutral platform for immediate review, reporting clinically actionable alerts with complete, bi-directional EHR integration.

The Bradenton, Florida-based company was founded in 2015 by cardiac rhythm management industry professionals Tripp Higgins — the current CEO — Ciprian Bordea, Jason Hale, Noemi Ray who experienced firsthand the overwhelming amount of device data inundating clinicians on a daily basis.

98. PhysicianXpressCategory: Healthcare Software

PhysicianXpress provides specialized medical revenue management for pediatric and specialty healthcare organizations. The company offers two services that make pediatric practices and specialty healthcare companies more efficient and easier to manage, leading to the highest profitability for its clients. Pediatric Xpress is an E.H.R. billing service designed by pediatricians for pediatric practices.

The clinical templates and work flow design of Pediatric Xpress allows doctors to complete well and sick visits with minimal time and effort while documenting developmental assessments. Spending more time with patients and less time completing more efficient paperwork helps doctors achieve the highest net profitability. PhysicianXpress was founded in 2007 by a pharmaceutical industry veteran who grew weary of his wife, a pediatrician with her own private practice, spending five hours every Sunday catching up on paperwork and losing thousands of dollars a month to inefficient billing and coding practices.

99. Momentum HealthwareCategory: Healthcare Software

Momentum Healthware specializes in the development, delivery, integration and support of seamless information technology software for the healthcare industry. Its solutions serve the information systems requirements of small to medium-sized hospitals, long-term care facilities, and the home care sector.

The company's healthcare solutions include RTLS in motion, assessment management system (both standardized assessments and interRAI assessments), convergence platform (a comprehensive software platform that puts all of your healthcare resources and patient information in one easy to use program).

The Canadian-based healthcare technology company was founded in 1995 by CEO Chuck LaFlèche, and has since grown to establish satellite offices located across Canada and the USA and partners in Australia, Ireland, and New Zealand.

The company's seamless information technology software provides electronic health records, assessments, registrations, clinical portals, dietary, pharmacy, real-time location, billing and decision support systems, enabling healthcare organizations to provide care to people in the continuum of long-term care facilities, home care and throughout the community.

100. Spine Software SystemsCategory: Healthcare Software

Spine Software Systems is an IT company, known for its enterprise resource planning (ERP) software for the pharmaceutical sector. Spine Software Systems works with a vision to interconnect the pharma sector through easy to use automated systems for better transparency, regulatory compliance and profitability. Spine is doing this by delivering highly successful IT products such as SPINE BMS, an exclusive Pharmaceutical industry ERP solution and PharmaTrader, a unique Pharmacy Management Solution.

Its portfolio stretches to IT services, such as enterprise software development, web designing & development and quality testing and assurance. Since its inception, it has grown into a full-fledged professionally managed IT company boasting of a list of satisfied clients in India and Europe. In addition, the company has handled a vast variety of projects including the complete automation of a Pharmaceutical manufacturing company starting from scratch, setting up Data Center infrastructure, designing and hosting websites, conversion of IT systems of a company from License based software to Open Source system and LAN/WAN management.

1. Johnson & Johnson 2. Integra LifeSciences 3. SOC Telemed 4. Danaher Corporation 5. Fresenius Medical Care 6. NextGen Healthcare 7. Castle Biosciences, Inc. 8. Boston Scientific 9. Vocera 10. Poseida Therapeutics, Inc. 11. PPD 12. GRAIL 13. Bardy Diagnostics 14. 3M Health Care 15. Cedar 16. RapidAI 17. HillRom 18. PartsSource 19. ImagineSoftware 20. Immunex 21. Ardelyx 22. DNA Script 23. Syneos Health 24. IBH Integrated Behavioral Health 25. Pulse Biosciences 26. Alltech 27. BioDelivery Sciences International Inc 28. Qventus 29. Biocon Biologics 30. PaxeraHealth 31. b.well Connected Health 32. Cerexa Inc. 33. Genuity Science 34. AKASA 35. Imclone Systems 36. Neptune Wellness Solutions 37. Phathom Pharmaceuticals 38. Meda Biotech 39. Vesta Healthcare 40. Promaxo 41. Pall Life Sciences 42. Mixlab 43. Edwards Lifesciences 44. SleepHive (formerly Revitalife) 45. Illumina, Inc. 46. ResMed 47. QIAGEN 48. Carestream Health 49. Meditech 50. Omnicell 51. Medidata 52. Adamed Group 53. Exos 54. JAZZ Pharmaceuticals 55. Inform Diagnostics 56. Abiomed 57. STEMCELL Technologies 58. Genmab 59. HealthStream 60. Halodoc 61. Carbon Health 62. Village MD 63. Lyra Health 64. Flatiron Health 65. Taconic Biosciences 66. Telstar 67. Certara 68. XACT Robotics 69. Alto Pharmacy 70. Capsule 71. AdvancedMD 72. EverlyWell 73. Unite Us 74. CMR Surgical 75. Surgical Information Systems 76. Atos Medical 77. Telcor 78. Aspen Surgical 79. Parsley Health 80. Kindbody 81. Centivo 82. Tytocare 83. Cricket Health 84. BioLife Solutions 85. eVisit Inc 86. RubiconMD 87. Abbot 88. ExplORer Surgical 89. Good Clean Love 90. Tivic Health 91. Kinnos 92. Vizzia Technologies 93. Neopharma Technologies Ltd 94. Neuro42 96. Dakota Software 97. PaceMate 98. PhysicianXpress 99. Momentum Healthware 100. Spine Software Systems